Lipstatin is a potent, irreversible inhibitor of pancreatic lipase. It is a natural product that was first isolated from the actinobacterium Streptomyces...
7 KB (568 words) - 10:19, 3 February 2024
provider-supervised reduced-calorie diet. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium...
39 KB (3,466 words) - 10:08, 22 May 2024
inhibitor lipstatin, of which the antiobesity drug orlistat is a derivative. Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H (1987). "Lipstatin, an inhibitor...
2 KB (161 words) - 23:24, 12 April 2024
and is a more simple and stable compound than lipstatin. For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. It...
27 KB (2,839 words) - 20:22, 2 August 2024