checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene. MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents...
8 KB (1,003 words) - 22:38, 27 December 2023
represent candidates for further evaluation." REV3L in turn interacts with MAD2L2 on Chromosome 1; thus the inheritance patter is likely to be more complicated...
22 KB (2,232 words) - 20:13, 27 September 2024
Humans proteins containing this domain include: HORMAD1, HORMAD2, MAD2L1, MAD2L2 He X, Patterson TE, Sazer S (1997). "The Schizosaccharomyces pombe spindle...
2 KB (202 words) - 14:31, 7 June 2023
sensitivity to microtubule poisons. The human orthologues of Mad2 (MAD2L1 and MAD2L2) were first cloned in a search for human cDNAs that would rescue the microtubule...
10 KB (1,150 words) - 15:42, 12 April 2024
Q9Y6D9 9086 MAD2L1 HGNC:6763 Q13257 9087 MAD2L1BP HGNC:21059 Q15013 9088 MAD2L2 HGNC:6764 Q9UI95 9089 MADCAM1 HGNC:6765 Q13477 9090 MADD HGNC:6766 Q8WXG6...
277 KB (17 words) - 18:41, 6 October 2024
polymerase, is made of two subunits Rev3, the catalytic subunit, and Rev7 (MAD2L2), which increases the catalytic function of the polymerase, and is involved...
59 KB (7,090 words) - 06:49, 30 June 2024
proteins, especially Pol ζ (Rev3/Rev7). REV1 has been shown to interact with MAD2L2. It is believed that Rev1 may interact with PCNA, once ubiquitylated due...
8 KB (1,093 words) - 13:00, 20 July 2024
two-hybrid screenings have found C20orf196 to interact with PRMT1, QARS, MAD2L2, and CUL3. C20orf196 functionally interacts with REV7, SHLD2, and SHLD3...
14 KB (1,446 words) - 01:25, 3 December 2023
chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome...
16 KB (1,975 words) - 22:35, 3 March 2023
chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2". Cell Cycle. 17 (1): 124–136. doi:10.1080/15384101.2017.1404210. ISSN 1538-4101...
30 KB (3,540 words) - 04:14, 2 November 2024