Obinutuzumab, sold under the brand name Gazyva among others, is a humanized anti-CD20 monoclonal antibody used as a treatment for cancer. It was originated...
18 KB (1,538 words) - 11:52, 27 August 2024
FDA granted accelerated approval to zanubrutinib, in combination with obinutuzumab, for relapsed or refractory follicular lymphoma after two or more lines...
23 KB (1,765 words) - 02:36, 28 April 2024
technology to afucosylate antibodies; one of its products in development was obinutuzumab, which gained FDA approval in November 2013 for the treatment of chronic...
57 KB (5,195 words) - 10:21, 4 November 2024
into a collaboration with Roche and its subsidiary GlycArt to develop obinutuzumab. In February 2010 Genentech entered into a collaboration with University...
32 KB (2,865 words) - 04:21, 4 October 2024
with obinutuzumab plus bendamustine followed by maintenance treatment with obinutuzumab (if they have not been treated previously with obinutuzumab). Other...
67 KB (7,967 words) - 13:33, 14 October 2024
actively controlled trial of venetoclax in combination with obinutuzumab (VEN+G) versus obinutuzumab in combination with chlorambucil (GClb) in 432 participants...
27 KB (2,575 words) - 15:22, 28 October 2024
non-Hodgkin's lymphoma (NHL). In January 2019, ibrutinib in combination with obinutuzumab was approved for the treatment of adults with previously untreated chronic...
29 KB (2,605 words) - 21:22, 16 August 2024
approval status: CD20 is the target of the mAbs rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which...
26 KB (2,953 words) - 04:22, 15 October 2024
Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory...
15 KB (1,046 words) - 20:02, 27 August 2024
Zurich. The first commercial product from the GlycArt acquisition was obinutuzumab, which as Gazyva gained FDA approval in November 2013 for the treatment...
6 KB (644 words) - 11:47, 13 December 2023