• Thumbnail for PLCG2
    phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. From OMIM as of March 24, 2020: Enzymes of the phospholipase C family...
    12 KB (1,405 words) - 12:49, 23 December 2023
  • Thumbnail for PLAID syndrome
    immune dysregulation, first described in 2012. The name is an acronym of "PLCG2-associated antibody deficiency and immune dysregulation". It is characterised...
    6 KB (711 words) - 20:19, 17 May 2023
  • Thumbnail for Cold urticaria
    phospholipase C-gamma2 (PLCG2), an enzyme involved in the activation of immune cells. The investigators have named the condition PLCG2-associated antibody...
    23 KB (2,547 words) - 18:38, 12 July 2024
  • Thumbnail for Bruton's tyrosine kinase
    has been shown to interact with: ARID3A BLNK (SLP-65), CAV1, GNAQ, GTF2I, PLCG2, PRKD1, and SH3BP5. GRCh38: Ensembl release 89: ENSG00000010671 – Ensembl...
    22 KB (2,389 words) - 06:43, 22 April 2024
  • Thumbnail for Phospholipase C
    have up to 30 PLC enzymes. beta: PLCB1, PLCB2, PLCB3, PLCB4 gamma: PLCG1, PLCG2 delta: PLCD1, PLCD3, PLCD4 epsilon: PLCE1 eta: PLCH1, PLCH2 zeta: PLCZ1...
    25 KB (2,691 words) - 00:59, 17 April 2024
  • Thumbnail for SH2 domain
    ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1; PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2; SH2B3; SH2D1A; SH2D1B; SH2D2A;...
    13 KB (1,341 words) - 04:09, 6 March 2024
  • Q9BRC7 12286 PLCE1 HGNC:17175 Q9P212 12287 PLCG1 HGNC:9065 P19174 12288 PLCG2 HGNC:9066 P16885 12289 PLCH1 HGNC:29185 Q4KWH8 12290 PLCH2 HGNC:29037 O75038...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for Platelet
    activation of a tyrosine kinase cascade finally to the activation of PLC-gamma2 (PLCG2) and more calcium release.[citation needed] Tissue factor also binds to...
    70 KB (8,414 words) - 23:19, 8 July 2024
  • Thumbnail for GAB2
    GAB2 (section PLCG2)
    GAB2, SHC, and SHP2 is required for binding of Phospholipase C gamma 2 (PLCG2) through its SH2 domain, which activates PIP3. Protein tyrosine phosphatase...
    26 KB (3,191 words) - 05:41, 17 June 2024
  • Thumbnail for Pleckstrin homology domain
    OSBPL9, PHLDA2, PHLDA3, PHLDB1, PHLDB2, PHLPP, PIP3-E, PLCD1, PLCD4, PLCG1, PLCG2, PLCH1, PLCH2, PLCL1, PLCL2, PLD1, PLD2, PLEK, PLEK2, PLEKHA1, PLEKHA2,...
    14 KB (1,434 words) - 15:11, 10 June 2024