Peripherally selective drugs have their primary mechanism of action outside of the central nervous system (CNS), usually because they are excluded from...
14 KB (1,496 words) - 02:26, 6 August 2024
Fexofenadine (redirect from Allegra (drug))
pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. Therapeutically, fexofenadine is a selective peripheral H1 blocker...
23 KB (2,161 words) - 22:59, 11 June 2024
Colchicine (category Peripherally selective drugs)
or preventing gout inflammation. Colchicine appears to be a peripherally selective drug with limited brain uptake due to binding to P-glycoprotein. The...
55 KB (5,703 words) - 04:45, 26 August 2024
Bilastine (category Peripherally selective drugs)
14.5 h and plasma protein binding of 84–90%. Bilastine is a peripherally selective drug, and this thought to be due to limited brain uptake caused by...
25 KB (2,626 words) - 16:57, 25 August 2024
Ondansetron (category Peripherally selective drugs)
highly selective serotonin 5-HT3 receptor antagonist, with low affinity for dopamine receptors. The 5-HT3 receptors are present both peripherally on vagal...
34 KB (3,154 words) - 19:29, 13 July 2024
Norepinephrine (medication) (redirect from Norepinephrine (drug))
blood–brain barrier under normal circumstances and hence is a peripherally selective drug. Norepinephrine is the INN while noradrenaline is the BAN. Andersen...
11 KB (622 words) - 05:24, 2 August 2024
Levocetirizine (category Peripherally selective drugs)
chiral switch of (±)-cetirizine. This enantiomer, the eutomer, is more selective and the (S)-counterpart, the distomer, is inactive. Chemically, levocetirizine...
15 KB (1,144 words) - 01:12, 30 July 2024
Bisoprolol (category Peripherally selective drugs)
no reported cases of clinically evident drug-induced liver injury associated with bisoprolol. Non-selective beta-blockers should be avoided in people...
31 KB (2,865 words) - 00:09, 26 August 2024
Loratadine (category Peripherally selective drugs)
Loratadine is a tricyclic antihistamine, which acts as a selective inverse agonist of peripheral histamine H1 receptors. The potency of second generation...
30 KB (2,563 words) - 05:06, 27 May 2024
Digoxin (category Peripherally selective drugs)
test for P-glycoprotein inhibition. Digoxin appears to be a peripherally selective drug due to limited brain uptake caused by binding to P-glycoprotein...
47 KB (4,845 words) - 07:24, 4 May 2024