Pirfenidone, sold under the brand name Pirespa among others, is a medication used for the treatment of idiopathic pulmonary fibrosis. It works by reducing...
39 KB (3,793 words) - 08:15, 23 June 2024
Idiopathic pulmonary fibrosis (section Pirfenidone)
pulmonary rehabilitation and supplemental oxygen. Certain medications like pirfenidone (Esbriet) or nintedanib (Ofev) may slow the progression of the disease...
71 KB (7,916 words) - 07:04, 27 August 2024
in mild idiopathic fibrosis are pirfenidone, which reduced reductions in the 1-year rate of decline in FVC. Pirfenidone also reduced the decline in distances...
31 KB (3,243 words) - 17:02, 4 July 2024
fibrosis) and 6.7 years in those with other types of ILD. The antifibrotics pirfenidone and nintedanib have been shown to slow the decline in lung function (as...
28 KB (2,840 words) - 18:55, 18 July 2024
Y, Wang Y, Wang C, Tian M, Gu X, Lv W (2021). "Inhibitory effect of pirfenidone on pulmonary fibrosis in patients with acute paraquat poisoning". Am...
46 KB (4,689 words) - 21:47, 8 September 2024
breakthrough therapy designation to receive FDA approval. 2014: Esbriet (pirfenidone): An anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis...
32 KB (2,862 words) - 04:08, 6 August 2024
idiopathic pulmonary fibrosis, certain medications like nintedanib and pirfenidone can help slow the progression. Lastly, lung transplants may help. Regardless...
11 KB (1,186 words) - 07:06, 27 August 2024
analgesia. Erivedge (vismodegib), for basal-cell carcinoma. Esbriet (pirfenidone), for idiopathic pulmonary fibrosis. Fansidar (sulfadoxine/pyrimethamine)...
55 KB (5,124 words) - 05:32, 27 August 2024
Sandoval-Rodriguez A, Monroy-Ramirez HC, Meza-Rios A, et al. (March 2020). "Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK"...
28 KB (2,324 words) - 14:34, 10 July 2024
Montes de Oca-Luna R, et al. (April 2020). "Efficacy and Safety of Pirfenidone in Patients with Second-Degree Burns: A Proof-of-Concept Randomized Controlled...
51 KB (6,166 words) - 01:23, 30 August 2024