Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that is encoded by the RIPK3 gene in humans. The product of this gene is a member of the receptor-interacting...
9 KB (952 words) - 03:02, 30 June 2024
TNF receptor-associated factor 2 TRAF2 signals to RIPK1 which recruits RIPK3 forming the necrosome also named ripoptosome. Phosphorylation of MLKL by...
14 KB (1,667 words) - 20:15, 23 April 2024
signalling. Via the intermediate domain, RIP can interact with TRAF2, NEMO, RIPK3, ZBP1, OPTN and other small molecules and proteins, depending on cellular...
35 KB (4,148 words) - 17:13, 8 June 2024
protein kinases. In humans, five different RIP kinases are known: RIPK1 RIPK2 RIPK3 RIPK4 RIPK5 Zhang, Duanwu; Lin, Juan; Han, Jiahuai (July 2010). "Receptor-interacting...
793 bytes (63 words) - 15:58, 23 December 2020
muscles become replaced by fat and fibrous tissue. A single study implicated RIPK3 in DUX4-mediated cell death. Unlike other muscular dystrophies, early muscle...
174 KB (16,344 words) - 19:36, 22 July 2024
undergo cell death via three main mechanisms: necroptosis via RIPK1, FADD, RIPK3, and MLKL, ferroptosis via GPX4 suppression, system Xc suppression, and...
8 KB (821 words) - 08:31, 9 October 2023
PTK6 ; PTK7 ; PXK ; RAF1 ; RET ; RIOK1 ; RIOK2 ; RIOK3 ; RIPK1 ; RIPK2 ; RIPK3 ; RIPK4 ; RNASEL ; ROCK1 ; ROCK2 ; ROR1 ; ROR2 ; ROS1 ; RPS6KA1 ; RPS6KA2 ;...
17 KB (1,559 words) - 03:23, 25 May 2024
Q8IUF8 13787 RIPK1 HGNC:10019 Q13546 13788 RIPK2 HGNC:10020 O43353 13789 RIPK3 HGNC:10021 Q9Y572 13790 RIPK4 HGNC:496 P57078 13791 RIPOR1 HGNC:25836 Q6ZS17...
282 KB (17 words) - 07:55, 20 June 2024
to integrate several molecular components, including ASC, caspase-8, and RIPK3. She then went on to establish that multiple PANoptosomes can contain different...
44 KB (4,323 words) - 10:21, 27 March 2024
inducers converge on receptor-interacting serine/threonine-protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL). Sequential activation...
19 KB (2,056 words) - 13:42, 25 May 2024