factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key...
19 KB (2,246 words) - 22:36, 11 April 2024
inherited in an autosomal dominant manner. It is due to a defect in the RUNX2 gene which is involved in bone formation. Diagnosis is suspected based on...
19 KB (1,675 words) - 04:56, 19 October 2024
genes that control this craniofacial development. Of these genes, DCHS2, RUNX2, GLI3, PAX1 and PAX3 were found to determine nasal morphology, whereas EDAR...
5 KB (421 words) - 00:13, 12 September 2023
of: a non-DNA-binding CBFβ chain (CBFB) a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3) de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis...
774 bytes (87 words) - 18:04, 28 November 2023
RUNX1 ENSG00000159216 Runt Known motif – In vivo/Misc source [787] VACCACAV RUNX2 ENSG00000124813 Runt Known motif – High-throughput in vitro [788] HRACCRCADWAACCRCAV...
374 KB (81 words) - 02:10, 23 September 2023
route of differentiation to osteoblast, rather than chondrocyte via the Runx2 gene expression. Potential therapeutic application in aiding bone degenerative...
25 KB (2,072 words) - 00:37, 4 October 2024
among bone-forming vertebrate species It plays a major role, along with Runx2 and Dlx5 in driving the differentiation of mesenchymal precursor cells into...
24 KB (2,875 words) - 03:59, 22 March 2024
et al. (19 May 2016). "A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation". Nature Communications....
32 KB (3,221 words) - 23:01, 5 October 2024
with: BCL3, COBRA1, CSNK2A1, CSNK2A2, DDIT3, JUN NCOA1, NCOR2, RELA, RUNX1, RUNX2, SMAD3, and TBP. Leptomycin c-Jun Egr-1 Ion channel G proteins & linked...
26 KB (3,991 words) - 05:29, 10 July 2024
S, et al. (April 2008). "Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells". Gene. 413...
16 KB (1,936 words) - 20:50, 10 October 2024