Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure...
181 KB (17,316 words) - 05:17, 7 September 2024
The pharmacodynamics of spironolactone, an antimineralocorticoid and antiandrogen medication, concern its mechanisms of action, including its biological...
97 KB (10,987 words) - 06:59, 1 September 2024
combination with other drugs, for the management of chronic heart failure. Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism...
15 KB (1,466 words) - 09:36, 13 December 2023
antagonists can also be used for treatment of primary hyperaldosteronism. Spironolactone, a steroidal aldosterone antagonist, is also used in management of female...
10 KB (1,057 words) - 02:50, 4 May 2024
reduced renal clearance. Eplerenone may have a lower incidence than spironolactone of sexual side effects such as feminization, gynecomastia, impotence...
17 KB (1,476 words) - 06:07, 17 June 2024
inhibitors finasteride and dutasteride and the steroidal AR antagonist spironolactone have been associated with significantly reduced risk of prostate cancer...
158 KB (15,079 words) - 13:02, 1 September 2024
Canrenone (category Spironolactone)
to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and...
14 KB (1,075 words) - 00:53, 5 August 2024
Generally, the starting dose is oral spironolactone 100 mg/day (max 400 mg/day). 40% of people will respond to spironolactone. For nonresponders, a loop diuretic...
26 KB (2,846 words) - 07:00, 24 August 2024
that have their effect at similar locations: Aldosterone antagonists: spironolactone, which is a competitive antagonist of aldosterone. Aldosterone normally...
23 KB (2,001 words) - 07:09, 22 June 2024
and spironolactone has mixed and inconsistent effects on hormone levels. In any case, testosterone levels are usually unchanged by spironolactone. Studies...
231 KB (25,180 words) - 16:37, 5 September 2024