channel subfamily M member 1 is a protein that in humans is encoded by the TRPM1 gene. The protein encoded by this gene is a member of the transient receptor...
9 KB (1,234 words) - 09:21, 7 March 2022
that both CSNB and leopard complex spotting patterns are linked to the TRPM1 gene. The region on horse chromosome 1 to which the Lp gene has now been...
9 KB (1,073 words) - 02:12, 31 July 2024
when LP is present. LP is an autosomal incomplete dominant mutation in the TRPM1 gene located at horse chromosome 1 (ECA 1). All horses with at least one...
73 KB (7,231 words) - 06:31, 29 July 2024
CSNB has been identified in horses and dogs as the result of mutations in TRPM1 (Horse, "LP"), GRM6 (Horse, "CSNB2"), and LRIT3 (Dog, CSNB). Congenital...
34 KB (2,878 words) - 04:07, 28 July 2024
team mapped the Lp gene to a transient receptor potential channel gene, TRPM1 or Melastatin 1 (MLSN1). The leopard complex allele contains a 1378 base-pair...
24 KB (2,603 words) - 07:45, 23 August 2024
to form tetramers. The TRPM family consists of eight different channels, TRPM1–TRPM8. Unlike the TRPC and TRPV sub-families, TRPM subunits do not contain...
7 KB (821 words) - 22:40, 16 July 2024
particular interest is the "genetic domestication selection at the horse TRPM1 coat-colour locus" as per the study. Although contemporaneous to Copper...
23 KB (2,222 words) - 00:49, 13 September 2024
indicated that both CSNB and leopard complex spotting patterns are linked to TRPM1. As this disorder also afflicts humans, a researcher and lead author from...
9 KB (858 words) - 22:00, 27 April 2024
sulfate is an agonist of the sigma receptor, as well as an activator of the TRPM1 and TRPM3 channels. It may also interact with potassium channels and voltage-gated...
6 KB (370 words) - 18:49, 6 May 2023
TPCN2 TRPA (channel) TRPC TRPC1 TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1...
15 KB (1,545 words) - 18:32, 17 August 2024