• Thumbnail for TRPM6
    TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia. TRPM Ruthenium red GRCh38: Ensembl release...
    2 KB (281 words) - 20:54, 20 June 2023
  • occurs by membrane transport through the TRPM6 ion channels and is crucial for magnesium homeostasis. TRPM6 is expressed on the part of the cell membrane...
    12 KB (1,033 words) - 04:04, 6 January 2024
  • homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been...
    93 KB (12,023 words) - 08:10, 10 June 2024
  • motifs but, rather, contain entire functional proteins in their C-termini. TRPM6 and TRPM7, for example, contain functional α-kinase segments, which are...
    7 KB (821 words) - 22:40, 16 July 2024
  • hypomagnesemia. Other genetic causes of hypomagnesemia, such as mutations in TRPM6, CNNM2, EGF, EGFR, KCNA1 or FAM111A. Many of the proteins encoded by these...
    45 KB (4,600 words) - 19:24, 6 August 2024
  • Thumbnail for Gitelman syndrome
    Na+/K+-ATPase. Indicated also are the recently identified magnesium channel TRPM6 in the apical membrane, and a putative Na/Mg exchanger in the basolateral...
    28 KB (2,941 words) - 22:23, 13 August 2024
  • Thumbnail for Magnesium in biology
    Konrad M, Gudermann T (2004). "Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia"...
    86 KB (10,448 words) - 22:13, 6 August 2024
  • Thumbnail for Ruthenium red
    These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1)...
    6 KB (487 words) - 19:02, 22 September 2023
  • and βTRPM. αTRPMs include vertebrate TRPM1, TRPM3, and the "chanzymes" TRPM6 and TRPM7, as well as the only insect TRPM channel, among others. βTRPMs...
    49 KB (5,517 words) - 22:16, 16 July 2024
  • Thumbnail for Alexey G. Ryazanov
    kinases that include elongation factor-2 kinase (eEF2K) and channel-kinases TRPM6 and TRPM7. Ryazanov and his colleagues demonstrated that eEF2K is a regulator...
    7 KB (673 words) - 22:55, 22 February 2024