Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase...
46 KB (5,303 words) - 08:02, 3 June 2024
A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by...
27 KB (3,043 words) - 03:16, 30 June 2024
Drosophila melanogaster lacks telomerase, but instead uses retrotransposons to maintain telomeres. Telomerase is a reverse transcriptase enzyme that carries its...
49 KB (5,644 words) - 06:05, 27 April 2024
HeLa (section Telomerase)
cells. Like many other cancer cells, HeLa cells have an active version of telomerase during cell division, which copies telomeres over and over again. This...
48 KB (5,642 words) - 15:16, 17 July 2024
studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after...
12 KB (1,044 words) - 23:32, 14 August 2024
mutation in motif D of the reverse transcriptase domain of the telomerase protein, hTERT, leads to this phenotype. Thus telomerase dosage is important for...
11 KB (1,181 words) - 01:44, 9 February 2024
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
61 KB (6,087 words) - 12:28, 10 August 2024
will facilitate or inhibit the activity. Although telomerase has telomerase reverse transcriptase as a catalytic subunit, regulation is accomplished...
8 KB (781 words) - 22:25, 19 March 2024
Cancer cell (section Telomerase)
features that make them "immortal" according to some researchers. The enzyme telomerase is used to extend the cancer cell's life span. While the telomeres of...
16 KB (1,727 words) - 06:01, 19 May 2024
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
125 KB (11,194 words) - 06:13, 15 August 2024