Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in...
98 KB (11,068 words) - 18:53, 17 August 2024
A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
24 KB (2,754 words) - 03:25, 27 May 2024
Proteasome (redirect from Ubiquitin proteosome system)
Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that...
105 KB (12,670 words) - 08:02, 23 August 2024
Ubiquitin is a protein that in humans is encoded by the UBB gene. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin...
8 KB (996 words) - 21:12, 21 June 2024
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target...
9 KB (1,051 words) - 15:40, 31 December 2023
Ubiquitin D is a protein that in humans is encoded by the UBD gene, also known as FAT10. UBD acts like ubiquitin, by covalently modifying proteins and...
17 KB (2,244 words) - 11:45, 4 January 2024
Ubiquitin-binding domains (UBDs) are protein domains that recognise and bind non-covalently to ubiquitin through protein-protein interactions. As of 2019...
6 KB (658 words) - 17:44, 22 June 2022
encoded by the UBC gene in humans. Polyubiquitin-C is one of the sources of ubiquitin, along with UBB, UBA52, and RPS27A. UBC gene is one of the two stress-regulated...
37 KB (4,261 words) - 21:30, 23 December 2023
Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step in the ubiquitination reaction...
5 KB (605 words) - 04:25, 28 November 2023
LUBAC (redirect from Linear ubiquitin chain assembly complex)
Linear ubiquitin chain assembly complex (LUBAC) is a multi-protein complex and the only known E3 ubiquitin ligase able to conjugate ubiquitin in a head-to-tail...
12 KB (1,247 words) - 08:33, 18 August 2023