A BBSome is a protein complex that operates in primary cilia biogenesis, homeostasis, and intraflagellar transport (IFT). The BBSome recognizes cargo proteins...
53 KB (6,700 words) - 03:20, 27 July 2024
BBS proteins are assembled into a multiple protein complex, called "BBSome". BBSome is proposed to be responsible for transporting intracellular vesicles...
15 KB (1,432 words) - 05:31, 17 June 2024
observed to drive the oligomerization of the BBS2 and BBS7 subunits of the BBSome. Because coiled-coils generally interact with other coiled coils, they are...
34 KB (3,860 words) - 04:15, 25 March 2024
(November 2011). "A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened". PLOS Genetics. 7 (11): e1002358. doi:10.1371/journal.pgen...
7 KB (561 words) - 03:27, 22 May 2024
protein that in humans is encoded by the BBS1 gene. BBS1 is part of the BBSome complex, which required for ciliogenesis. Mutations in this gene have been...
6 KB (784 words) - 13:28, 18 October 2022
molecular function Cellular component cytoplasm cytosol cell projection BBSome pericentriolar material membrane plasma membrane cilium centriolar satellite...
4 KB (498 words) - 06:59, 27 March 2022
cilia, intraflagellar transport proteins such as IFT57 and ARF4 while the BBSome does not appear to interact with the sequence. The kinesins KIF17 is implicated...
14 KB (1,462 words) - 04:36, 26 April 2024
binding protein binding Cellular component cytoplasm cytosol cell projection BBSome membrane plasma membrane cilium intracellular anatomical structure microtubule...
8 KB (707 words) - 01:07, 29 April 2024
component cytoplasm ciliary basal body cytosol centrosome cell projection BBSome membrane plasma membrane photoreceptor outer segment cilium microtubule...
4 KB (546 words) - 21:55, 18 August 2023
Cellular component cytoplasm ciliary basal body cytosol cell projection BBSome membrane plasma membrane cilium microtubule organizing center ciliary membrane...
7 KB (687 words) - 04:33, 30 January 2023