Cullin-4B is a protein that in humans is encoded by the CUL4B gene which is located on the X chromosome. CUL4B has high sequence similarity with CUL4A, with which...

larger subunit DDB1 primarily functions as a core component of CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. Substrates that are ubiquitinnated...

HGNC:2552 Q13617 3795 CUL3 HGNC:2553 Q13618 3796 CUL4A HGNC:2554 Q13619 3797 CUL4B HGNC:2555 Q13620 3798 CUL5 HGNC:2556 Q93034 3799 CUL7 HGNC:21024 Q14999...

humans is encoded by the DCAF15 gene. DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase activity and is responsible for the proteasome...

complex (Elongin C - CUL2 - SOCS-box) CUL3, part of CUL3-BTB complex CUL4A CUL4B CUL5 CUL7 CUL9, also known as PARC There is also a more distant member called...

cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin...

found that DDB1 primarily functions as a core component of the CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. DDB1 serves as a bridge or adaptor...

protein-containing complex binding Cellular component nucleoplasm cell junction Cul4B-RING E3 ubiquitin ligase complex nucleus Cul4-RING E3 ubiquitin ligase complex...

microtubule organizing center nucleolus Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex cytoskeleton nucleus nucleoplasm cytoplasm...

CAND1 gene. CAND1 has been shown to interact with: CUL1, CUL2, CUL3, CUL4A, CUL4B, DCUN1D1, and RBX1. GRCh38: Ensembl release 89: ENSG00000111530 – Ensembl...