Ceramidase (EC 3.5.1.23, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing...
3 KB (328 words) - 13:29, 26 August 2023
Farber disease (redirect from Ceramidase deficiency)
Farber disease (also known as Farber's lipogranulomatosis, acid ceramidase deficiency, "Lipogranulomatosis", and ASAH1-related disorders) is an extremely...
14 KB (1,401 words) - 06:58, 15 April 2024
ASAH1 (redirect from Acid ceramidase)
The ASAH1 gene encodes in humans the acid ceramidase enzyme. This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and...
10 KB (1,273 words) - 20:11, 7 November 2023
the generation of ceramides. Ceramide can be further hydrolyzed by acid ceramidase to form sphingosine and a free fatty acid, both of which are able to leave...
29 KB (3,310 words) - 03:20, 2 February 2024
Rivera. The ASAH1 gene codes for acid ceramidase, an enzyme found in lysosomes. The lysosome breaks down acid ceramidase; the fatty acid component is then...
7 KB (514 words) - 09:50, 18 March 2024
causing buildup. Lysosomal storage diseases include: Sphingolipidoses Ceramidase Farber disease Krabbe disease Infantile onset Late onset Galactosialidosis...
18 KB (1,819 words) - 05:23, 3 April 2024
be the generation of 5–FU. However, carmofur is a highly potent acid ceramidase (AC) inhibitor. Ceramide influences cancer cell survival, growth and death...
9 KB (836 words) - 22:04, 8 January 2024
generated by this process. Finally, ceramide may be broken down by a ceramidase to form sphingosine. Sphingosine may be phosphorylated to form sphingosine-1-phosphate...
24 KB (2,693 words) - 23:05, 9 June 2024
Neutral ceramidase is an enzyme that in humans is encoded by the ASAH2 gene. GRCh38: Ensembl release 89: ENSG00000188611 – Ensembl, May 2017 GRCm38: Ensembl...
5 KB (687 words) - 23:03, 6 February 2024
SPTTooltip Serine C-palmitoyltransferase Myriocin Ceramidase Ceranib 1 OEA SphKTooltip Sphingosine kinase N,N-DMS Safingol SKI II...
14 KB (828 words) - 06:35, 7 July 2024