Cyclin-K is a protein that in humans is encoded by the CCNK gene. The protein encoded by this gene is a member of the transcription cyclin family. These...
8 KB (1,042 words) - 23:25, 3 January 2024
of a protein kinase, cyclin-dependent kinase (CDK), with a regulatory subunit, cyclin. Once cyclin-dependent kinases bind to cyclin, the formed complex...
18 KB (2,258 words) - 22:16, 16 December 2023
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,830 words) - 17:52, 29 January 2025
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally...
19 KB (1,763 words) - 01:41, 23 January 2025
regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible...
12 KB (1,460 words) - 23:03, 27 March 2024
Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
35 KB (4,314 words) - 00:26, 6 July 2024
Cyclin D is a member of the cyclin protein family that is involved in regulating cell cycle progression. The synthesis of cyclin D is initiated during...
39 KB (4,605 words) - 21:40, 11 December 2024
screening revealed structurally diverse molecular glue degraders targeting cyclin K. The discovery that manumycin polyketides acted as molecular glues, fostering...
38 KB (3,873 words) - 01:15, 30 January 2025
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk...
11 KB (1,334 words) - 23:16, 17 December 2024
Cyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle...
14 KB (1,638 words) - 18:17, 27 April 2024