it is encoded by the DNMT1 gene. Dnmt1 forms part of the family of DNA methyltransferase enzymes, which consists primarily of DNMT1, DNMT3A, and DNMT3B...
19 KB (2,381 words) - 11:49, 28 March 2024
DNA methyltransferase (section DNMT1)
required for the catalytic function of DNMT1.[citation needed] DNMT1 has several isoforms, the somatic DNMT1, a splice variant (DNMT1b) and an oocyte-specific...
33 KB (3,598 words) - 17:16, 28 March 2024
DNA methyltransferase-1 (DNMT1). This phosphorylation causes movement of DNMT1 to the nucleus, where it can be transcribed. DNMT1 recruits other DNMTs, including...
63 KB (7,473 words) - 11:32, 1 September 2024
it is now known that DNMT1 physically interacts with the protein UHRF1. UHRF1 has been recently recognized as essential for DNMT1-mediated maintenance...
161 KB (18,346 words) - 02:11, 20 August 2024
DNMTs in humans: DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L, and in algae and fungi 3 more are present (DNMT4, DNMT5, and DNMT6). DNMT1 contains the replication...
23 KB (2,630 words) - 08:55, 2 September 2024
which are found in cigarette smoke. DNMT1 is the enzyme involved in the maintenance of DNA methylation marks. DNMT1 is recruited to DNA during its replication...
14 KB (1,902 words) - 19:47, 29 June 2024
family of DNA methyltransferase enzymes, which consists of the protagonists DNMT1, DNMT3A and DNMT3B. While de novo DNA methylation modifies the information...
34 KB (3,924 words) - 10:55, 28 March 2024
Klein, C. J., Botuyan, M. V., Wu, Y.; et al. (Jun 2011). "Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss". Nature...
29 KB (3,744 words) - 10:41, 12 August 2024
5 to 12.5 DNMT3a and DNMT3b are repressed and DNMT1 is present in the nucleus at a high level. But DNMT1 is unable to methylate cytosines during days 9...
42 KB (5,154 words) - 13:37, 14 February 2024
DNMT1. DNMT1 aids in regulation of gene expression by methylating promoter regions of genes, causing transcriptional repression of these genes. DNMT1...
97 KB (11,227 words) - 20:18, 19 July 2024