the ERBB3 gene. ErbB3 is a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is...
24 KB (2,816 words) - 06:51, 2 November 2024
Proliferation-associated protein 2G4 (PA2G4) also known as ErbB3-binding protein 1 (EBP1) is a protein that in humans is encoded by the PA2G4 gene. This...
10 KB (1,255 words) - 02:03, 8 April 2024
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:...
42 KB (3,935 words) - 20:28, 27 October 2024
able to interact, they trigger an activation loop. As a result, the ErbB2/ErbB3 signaling pathway becomes constitutively activated, cell–cell interactions...
20 KB (2,270 words) - 13:39, 28 October 2024
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:...
68 KB (5,999 words) - 00:04, 25 October 2024
In humans, the family includes Her1 (EGFR, ErbB1), Her2 (ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a...
24 KB (2,736 words) - 00:12, 28 November 2023
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:...
92 KB (8,729 words) - 03:44, 26 October 2024
effects on the glass transition. Radhakrishnan's 2010 paper investigated ErbB3/HER3 kinase activity, revealing its capacity for autophosphorylation and...
13 KB (1,323 words) - 21:54, 21 August 2024
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:...
149 KB (15,703 words) - 20:22, 18 October 2024
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:...
18 KB (1,573 words) - 05:19, 15 October 2024