• An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells...
    22 KB (2,564 words) - 17:36, 18 September 2024
  • Thumbnail for Epitope mapping
    In immunology, epitope mapping is the process of experimentally identifying the binding site, or epitope, of an antibody on its target antigen (usually...
    23 KB (2,661 words) - 04:37, 28 April 2024
  • Epitope binning is a competitive immunoassay used to characterize and then sort a library of monoclonal antibodies against a target protein. Antibodies...
    2 KB (261 words) - 16:41, 26 April 2024
  • In immunology, cryptic self epitopes are a source of autoimmunity. Self epitopes, which are found in high concentration on the surface of antigen-presenting...
    1 KB (156 words) - 20:40, 2 July 2023
  • Thumbnail for Linear epitope
    In immunology, a linear epitope (also sequential epitope) is an epitope—a binding site on an antigen—that is recognized by antibodies by its linear sequence...
    4 KB (408 words) - 08:07, 4 January 2023
  • Thumbnail for Conformational epitope
    In immunology, a conformational epitope is a sequence of sub-units (usually amino acids) composing an antigen that come in direct contact with a receptor...
    3 KB (291 words) - 23:24, 26 November 2022
  • Thumbnail for Antigen
    constitutes an epitope. Most antigens have the potential to be bound by multiple antibodies, each of which is specific to one of the antigen's epitopes. Using...
    20 KB (2,437 words) - 23:07, 19 August 2024
  • Thumbnail for Polyclonal B cell response
    antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell. In the course of normal immune response...
    49 KB (5,613 words) - 10:01, 27 March 2024
  • Thumbnail for Immunofluorescence
    antibody recognizes on an antigen is called an epitope. Several antibodies can recognize the same epitope but differ in their binding affinity. The antibody...
    21 KB (2,054 words) - 16:47, 21 April 2024
  • Thumbnail for Autoimmunity
    self-tolerance. Epitope spreading or epitope drift – when the immune reaction changes from targeting the primary epitope to also targeting other epitopes. In contrast...
    50 KB (5,851 words) - 16:28, 29 July 2024