humans, the family includes Her1 (EGFR, ErbB1), Her2 (ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a viral...
24 KB (2,736 words) - 00:12, 28 November 2023
HER2 (redirect from ErbB-2 receptor)
tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic...
43 KB (4,651 words) - 13:41, 27 July 2024
Epidermal growth factor receptor (redirect from Oncogene proteins v-erbb)
of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her...
60 KB (6,879 words) - 14:26, 16 July 2024
ERBB3 (redirect from Receptor, erbb-3)
(EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is known to form active heterodimers with other members of the ErbB family...
23 KB (2,751 words) - 14:34, 6 June 2024
different RTK classes have been identified. RTK class I (EGF receptor family) (ErbB family) RTK class II (Insulin receptor family) RTK class III (PDGF receptor...
28 KB (3,078 words) - 07:46, 3 June 2024
Erb's palsy is a paralysis of the arm caused by injury to the upper group of the arm's main nerves, specifically the severing of the upper trunk C5–C6...
16 KB (1,961 words) - 12:18, 19 July 2024
Look up Erb, erb, or 'erb in Wiktionary, the free dictionary. Erb, ERB or ErB may refer to: Edgar Rice Burroughs (1875–1950), American author Erb of Gwent...
3 KB (360 words) - 22:08, 31 January 2024
all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms...
32 KB (3,921 words) - 10:13, 27 March 2024
wild-type EGFR that are expected to lead to a wider therapeutic index. The pan-ErbB inhibitor Neratinib was approved in the US in 2017 and in the EU in 2018...
20 KB (2,061 words) - 05:47, 29 November 2023