• Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids...
    7 KB (544 words) - 13:50, 5 June 2024
  • Thumbnail for Glucuronic acid
    hydroxyl groups. This linkage process is known as glucuronidation (or glucuronide conjugation). Glucuronidation occurs mainly in the liver, although the enzymes...
    17 KB (1,882 words) - 14:14, 7 August 2024
  • Thumbnail for Glucuronosyltransferase
    of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction. Alternative names: glucuronyltransferase UDP-glucuronyl transferase...
    7 KB (679 words) - 22:07, 1 August 2024
  • Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with...
    5 KB (556 words) - 03:32, 1 February 2024
  • Thumbnail for Desloratadine
    3-hydroxydesloratadine in a three-step sequence in normal metabolizers. First, N-glucuronidation of desloratadine by UGT2B10; then, 3-hydroxylation of desloratadine...
    14 KB (1,039 words) - 04:17, 1 June 2024
  • Thumbnail for Bromazolam
    bromazolam glucuronide, were detected as phase II metabolites. Bromazolam N-glucuronidation was found to be catalysed by UGT1A4 and UGT2B10.  The formation of...
    19 KB (2,022 words) - 23:29, 11 September 2024
  • Thumbnail for Glucuronide
    via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method...
    2 KB (173 words) - 21:50, 31 December 2020
  • Thumbnail for Triamcinolone
    6-hydroxy- and 20-dihydro-triamcinolone; most of it probably undergoes glucuronidation, and a smaller part sulfation. Three quarters are excreted via the...
    19 KB (1,502 words) - 00:52, 30 September 2024
  • Thumbnail for Carvedilol
    CYP2D6 and CYP2C9 via aromatic ring oxidation and glucuronidation, then further conjugated by glucuronidation and sulfation. The three active metabolites exhibit...
    33 KB (2,908 words) - 03:30, 7 September 2024
  • Thumbnail for Galantamine
    One of the metabolites that may result can be formed through the glucuronidation of galantamine. Additionally, galantamine may undergo oxidation or...
    35 KB (3,136 words) - 06:43, 7 September 2024