(IRS-1) is a signaling adapter protein that in humans is encoded by the IRS1 gene. It is a 131 kDa protein with amino acid sequence of 1242 residues....

but were discovered with a 12" telescope. An infrared and radio source, IRS1, 3.3" from σ Ori A that was considered to be a patch of nebulosity has been...

PKC-θ by diacylglycerol may cause insulin resistance in muscle by decreasing IRS1-associated PI3K activity. Similarly, activation of PKCε by diacyglycerol...

in humans is encoded by the FBXO40 gene. Fbxo40 induces ubiquitination of IRS1, thus limiting activity of IGF1 signaling (Shi et al, 2011). Members of the...

There have been numerous reported protein substrates for PTEN, including IRS1 and Dishevelled. PTEN appears to play a critical role in the DNA damage response...

PTB-domain binds the NPXY sequence. Thus, the insulin receptor binds IRS. IRS1 (see also Insulin receptor substrate 1) IRS2 (see also Insulin receptor substrate...

BMF, BNIP2, BNIP3, BNIPL, BAD BAX, BIK, C-Raf, CAPN2, CASP8, Cdk1, HRK, IRS1, Myc, NR4A1, Noxa, PPP2CA, PSEN1, RAD9A, RRAS, RTN4, SMN1, SOD1, and TP53BP2...

of glucose homeostasis, including the phosphorylation of insulin receptor IRS1 and of the gluconeogenic enzymes phosphoenolpyruvate carboxykinase and glucose...

GRB2-related adaptor protein 2 GRB2 – Growth factor receptor-bound protein 2 IRS1 – Insulin receptor substrate 1 LDLRAP1 – low-density lipoprotein receptor...

HGNC:28835 Q6NXR0 7788 IRGM HGNC:29597 A1A4Y4 7789 IRGQ HGNC:24868 Q8WZA9 7790 IRS1 HGNC:6125 P35568 7791 IRS2 HGNC:6126 Q9Y4H2 7792 IRS4 HGNC:6128 O14654 7793...