LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in humans is encoded by the LMO2 gene...
15 KB (1,826 words) - 17:25, 2 October 2024
close proximity of the inserted gene to the LMO2 promoter, which controls the transcription of the LMO2 proto-oncogene. Hybrid Fusion protein Gene pool...
29 KB (3,583 words) - 18:09, 29 April 2024
HGNC:26683 Q8N9Z9 8789 LMNTD2 HGNC:28561 Q8IXW0 8790 LMO1 HGNC:6641 P25800 8791 LMO2 HGNC:6642 P25791 8792 LMO3 HGNC:6643 Q8TAP4 8793 LMO4 HGNC:6644 P61968 8794...
277 KB (17 words) - 18:41, 6 October 2024
disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted. LMO1 has been shown to interact with GATA3 and TAL1. GRCh38:...
9 KB (1,258 words) - 20:36, 27 December 2023
"Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4". EMBO J. 22 (9): 2224–33. doi:10.1093/emboj/cdg196. ISSN 0261-4189...
9 KB (1,074 words) - 19:29, 23 April 2024
PMID 15958283. Han C, Liu H, Liu J, et al. (2005). "Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex"...
5 KB (543 words) - 06:12, 1 December 2023
respectively. Lmo2 is associated with T-cell leukemias, and is also essential to erythropoiesis in early developmental stages, as Lmo2 knockout mice experience...
26 KB (3,172 words) - 15:28, 13 May 2024
Schmidt M, McCormack MP, Wulffraat N, Leboulch P, et al. (October 2003). "LMO2-associated clonal T cell proliferation in two patients after gene therapy...
60 KB (8,340 words) - 05:00, 22 July 2024
leukemia due to insertion of the IL2RG gene near the LMO2 gene and thereby activating the LMO2 gene (a known oncogene). A third child developed leukemia...
36 KB (4,335 words) - 20:14, 12 July 2024
Peschle C, Marziali G (April 2009). "MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis". Haematologica. 94 (4): 479–86. doi:10.3324/haematol...
5 KB (656 words) - 09:21, 10 March 2024