Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin...
9 KB (1,138 words) - 00:32, 9 November 2023
Function-associated Antigen 1, also called αLβ2 integrin Mac1 (CD11b/CD18) present on macrophages that is also called Macrophage-1 antigen (CR3) and αMβ2 integrin...
1,012 bytes (87 words) - 01:41, 12 July 2023
members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 such as LFA-1 and Macrophage-1 antigen, during inflammation...
2 KB (156 words) - 10:59, 24 June 2024
lymphocytes. For example, they are important as antigen presenters to T cells. In humans, dysfunctional macrophages cause severe diseases such as chronic granulomatous...
92 KB (10,131 words) - 14:06, 1 July 2024
CR3 or CR-3 may refer to: Macrophage-1 antigen, an immunological cell surface receptor for a complement component CR3, an x86 microprocessor control register...
791 bytes (138 words) - 23:04, 26 September 2022
can present antigens in some way. They are found in a variety of tissue types. Dedicated antigen-presenting cells, including macrophages, B cells and...
16 KB (2,128 words) - 09:55, 4 March 2024
evidenced by downregulated expression of the phagocytic receptor Macrophage 1 antigen (Mac-1). AMs actively suppress the induction of two of the immunity...
33 KB (3,862 words) - 16:23, 12 June 2024
Integrin alpha M (redirect from Antigens, cd11b)
heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A...
15 KB (1,716 words) - 17:02, 7 November 2023
subtype. M2a macrophages are activated by IL-4 and IL-13 which evokes upregulated expression of arginase-1, mannose receptor MRc1 (CD206), antigen presentation...
26 KB (3,077 words) - 07:06, 18 October 2023
receptors bind effector protein fragments that are produced in response to antigen-antibody complexes or damage-associated molecules. Complement receptor...
6 KB (376 words) - 06:42, 5 March 2024