(PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the PDK2 gene. PDK2 is...
16 KB (1,929 words) - 07:41, 4 January 2024
PHLPP (section Phosphorylation of Akt by PDK1 and PDK2)
activity. The PHLPPs therefore antagonize PDK1 and PDK2, since they dephosphorylate the site that PDK2 phosphorylates. PHLPP1 and 2 also dephosphorylate...
12 KB (1,456 words) - 23:51, 18 June 2024
At site 1 in order from fastest to slowest, PDK2 > PDK4 ≈ PDK1 > PDK3. For site 2, PDK3 > PDK4 > PDK2 > PDK1. Only PDK1 can phosphorylate site 3. However...
14 KB (1,711 words) - 16:27, 25 October 2023
Metal transporter CNNM3 (section Transcriptional regulation of CNNM3 by PDK2 in lung adenocarcinoma)
been prove that CNNM3 is one of the most correlated genes to PDK2 in lung adenocarcinoma. PDK2 regulates the activity of the CNNM3 promoter in lung adenocarcinoma...
14 KB (1,708 words) - 16:25, 24 May 2024
first by mTORC2. mTORC2 therefore functionally acts as the long-sought PDK2 molecule, although other molecules, including integrin-linked kinase (ILK)...
35 KB (3,831 words) - 18:08, 20 August 2024
EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated...
3 KB (296 words) - 17:06, 14 September 2023
EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated...
46 KB (5,492 words) - 14:52, 20 August 2024
EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated...
65 KB (7,149 words) - 04:45, 26 August 2024
EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated...
48 KB (5,285 words) - 16:26, 21 August 2024
EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated...
69 KB (7,803 words) - 11:01, 11 April 2024