Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
19 KB (2,170 words) - 06:41, 27 May 2024
Rho-kinase inhibitors (rho-associated protein kinase inhibitor or ROCK inhibitor) are a series of compounds that target rho kinase (ROCK) and inhibit the...
15 KB (1,642 words) - 20:05, 31 August 2023
acts upon several effectors. Among them, ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 (Diaphanous Homologue 1, a.k.a. hDia1...
45 KB (5,373 words) - 10:46, 29 June 2024
gene. The DMPK gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies...
19 KB (2,426 words) - 16:47, 30 March 2024
RhoC (Ras homolog gene family, member C) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of...
16 KB (1,931 words) - 14:01, 2 November 2024
While it is known that myosin phosphatase is regulated by rho-associated protein kinases, there is current debate about whether other molecules, such...
14 KB (1,600 words) - 15:01, 26 August 2023
Y-27632 (category Protein kinase inhibitors)
the rho-associated protein kinase (ROCK) signaling pathways. Y-27632 selectively inhibits p160ROCK, although it does inhibit other protein kinases such...
6 KB (426 words) - 16:50, 19 June 2024
Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein...
1 KB (213 words) - 21:30, 3 March 2023
Chicago, Rock Island and Pacific Railroad Rho-associated protein kinase, a serine/threonine-specific protein kinase Rollergirls of Central Kentucky, roller...
513 bytes (97 words) - 17:46, 29 September 2022
superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated...
14 KB (1,759 words) - 17:22, 10 April 2024