• Thumbnail for Adeno-associated virus
    Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in...
    72 KB (8,401 words) - 06:44, 28 August 2024
  • Self-complementary adeno-associated virus (scAAV) is a viral vector engineered from the naturally occurring adeno-associated virus (AAV) to be used as...
    11 KB (1,279 words) - 13:39, 7 September 2023
  • Thumbnail for Viral vector
    vaccine, and the Janssen vaccine. Adeno-associated viruses (AAVs) are relatively small single-stranded DNA viruses belonging to Parvoviridae and, like...
    48 KB (5,532 words) - 12:43, 9 October 2024
  • Thumbnail for Spinal muscular atrophy
    as Zolgensma) is a gene therapy treatment which uses self-complementary adeno-associated virus type 9 (scAAV-9) as a vector to deliver the SMN1 transgene...
    89 KB (9,948 words) - 05:18, 19 October 2024
  • MJ, Nickerson DM, Colahan PT, Ghivizzani SC (2018). "Self-Complementary Adeno-Associated Virus-Mediated Interleukin-1 Receptor Antagonist Gene Delivery...
    45 KB (5,381 words) - 18:10, 29 October 2024
  • peripheral organs, such as a muscle or gland. Certain viruses, such as adeno-associated virus, can be injected into the bloodstream and can cross the...
    20 KB (2,593 words) - 13:56, 24 January 2024
  • exogenously derived small interfering RNA (siRNA) induces the degradation of complementary messenger RNA. Other classes of small RNA have been identified, including...
    47 KB (5,449 words) - 12:35, 27 October 2024
  • are the same or different. Homotelomeric parvoviruses such as adeno-associated viruses (AAV), i.e. those that have identical or similar telomeres, have...
    54 KB (7,421 words) - 14:47, 19 September 2024
  • lymphoid tumors. Adeno-associated virus (AAV) vectors are considered low-risk for host-genome integration, as AAV infection has not been associated with the induction...
    25 KB (2,366 words) - 16:23, 18 October 2024
  • Thumbnail for CRISPR gene editing
    such as those based on lentivirus (LVs), adenovirus (AdV), and adeno-associated virus (AAV). Efficiency of CRISPR-Cas9 has been found to greatly increase...
    170 KB (19,884 words) - 03:21, 28 October 2024