A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy...

smaller than Fab fragments (~50 kDa, one light chain and half a heavy chain) and single-chain variable fragments (~25 kDa, two variable domains, one from...

a pFc' fragment The variable regions of the heavy and light chains can be fused together to form a single-chain variable fragment (scFv), which is only...

against specific targets. The most commonly used form is the single chain variable fragment (scFv), which has shown the most promising traits exploitable...

region (one arm) Variable fragments: scFv: single-chain variable fragment di-scFv: dimeric single-chain variable fragment sdAb: single-domain antibody...

between each chain. The "knobs-into-holes" shape facilitates antibody dependent cell mediated cytotoxicity. Single-chain variable fragments (scFv) are connected...

experimental anti-cancer medication. Chemically, oportuzumab is a single chain variable fragment of a monoclonal antibody which binds to epithelial cell adhesion...

angioplasty, among other types of cardiac surgery. It is a single chain variable fragment of a monoclonal antibody targeted against component 5 of the...

two single-chain variable fragments (scFvs) of different antibodies, or amino acid sequences from four different genes, on a single peptide chain of about...

product safety and quality issues. Chemically, efungumab is a single-chain variable fragment of a human monoclonal antibody. As such, it "grabs" onto fungal...