Small GTPases (EC 3.6.5.2), also known as small G-proteins, are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP)...
4 KB (503 words) - 09:22, 21 October 2023
GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP)...
20 KB (2,306 words) - 18:17, 15 July 2024
All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal...
34 KB (4,040 words) - 14:34, 19 July 2024
GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and...
16 KB (2,237 words) - 20:38, 22 July 2024
G protein (section Small GTPases)
larger group of enzymes called GTPases. There are two classes of G proteins. The first function as monomeric small GTPases (small G-proteins), while the second...
24 KB (2,754 words) - 20:56, 30 July 2024
Small GTPAses is a peer-reviewed scientific journal covering research on small GTPases, including their structural biology, biochemical regulation, and...
2 KB (77 words) - 22:49, 26 April 2023
family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have...
25 KB (3,198 words) - 05:03, 22 June 2024
is a small (~21 kDa) signalling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Members...
29 KB (3,420 words) - 21:45, 4 April 2024
proteins such as the syntaxin homolog Vam3, SNAP-25 homolog Vam7, Ras-like GTPase Ypt7, and the NSF ortholog, Sec18. Several complexes are known to flexibly...
53 KB (6,566 words) - 03:25, 8 July 2024
of Rho GTPase signaling is implicated in the process of carcinogenesis, and highlighted the critical role of several members of the small GTPase superfamily...
14 KB (1,539 words) - 05:34, 1 January 2024