Alpha-synuclein (aSyn) is a protein that, in humans, is encoded by the SNCA gene. Alpha-synuclein is a neuronal protein that regulates synaptic vesicle...
83 KB (9,387 words) - 23:27, 26 September 2024
electric ray. The synuclein family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. Interest in the synuclein family began...
5 KB (491 words) - 03:14, 29 November 2023
radiating fibrils, the primary structural component of which is alpha-synuclein (α-synuclein). In 1910, Fritz Heinrich Lewy was studying in Berlin for his doctorate...
15 KB (1,687 words) - 19:22, 11 July 2024
initial clinical manifestation of the disorder. A prion of the alpha-synuclein protein within affected neurons may cause MSA. About 55% of MSA cases...
45 KB (4,807 words) - 04:09, 19 September 2024
Beta-synuclein is a protein that in humans is encoded by the SNCB gene. The protein encoded by this gene is highly homologous to alpha-synuclein. These...
10 KB (1,165 words) - 12:49, 26 November 2023
Gamma-synuclein is a protein that in humans is encoded by the SNCG gene. Synuclein-gamma is a member of the synuclein family of proteins, which are believed...
9 KB (1,104 words) - 13:23, 26 November 2023
diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. There are three main...
12 KB (1,300 words) - 23:27, 26 September 2024
lungs and kidney, resulting high toxicity; as well, as death. Alpha-synuclein (α-synuclein) is an endogenous protein that is encoded by the SNCA gene and known...
29 KB (3,147 words) - 15:08, 26 November 2023
Parkinson's disease-associated mutant alpha-synucleins through axons of cultured neurons. Membrane damage by alpha-synuclein could be another Parkinson's disease...
63 KB (6,939 words) - 02:47, 2 September 2024
The cause of this cell death is poorly understood but involves alpha-synuclein aggregation into Lewy bodies within the neurons. Other possible factors...
169 KB (18,337 words) - 14:51, 27 September 2024