Thymidine phosphorylase (EC 2.4.2.4) is an enzyme that is encoded by the TYMP gene and catalyzes the reaction: thymidine + phosphate ⇌ {\displaystyle \rightleftharpoons...

ingredients: trifluridine, a nucleoside analog, and tipiracil, a thymidine phosphorylase inhibitor. Tipiracil prevents rapid metabolism of trifluridine...

caused by mutations in the TYMP gene, which encodes the enzyme thymidine phosphorylase. Mutations in this gene result in impaired mitochondrial function...

TYMP is a gene that encodes for the enzyme thymidine phosphorylase. The TYMP gene is also known as ECGF1 (endothelial cell growth factor 1, platelet-derived)...

Pyrimidine phosphorylase may refer to: Thymidine phosphorylase Uridine phosphorylase This article includes a list of related items that share the same...

can phosphorylate into uridine triphosphate. Thymidine phosphorylase or pyrimidine-nucleoside phosphorylase adds 2-deoxy-alpha-D-ribose 1-phosphate to thymine...

the blood concentration of trifluridine by inhibiting the enzyme thymidine phosphorylase which metabolizes trifluridine. Adverse effects were not assessed...

His 118-page thesis was entitled "Kinetic Isotope Effects of Thymidine Phosphorylase"; the research focused on the kinetics of a glycosyltransferase...

digestive system. Within a cell, pyrimidine nucleoside phosphorylase or thymidine phosphorylase can metabolize doxifluridine into 5-FU. It is also a metabolite...

influence blood plasma concentrations of trifluridine. Being a thymidine phosphorylase inhibitor, trifluridine could also interact with substrates of...