Tolerogenic dendritic cells (a. k. a. tol-DCs, tDCs, or DCregs) are heterogenous pool of dendritic cells with immuno-suppressive properties, priming immune...

A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system. A DC's main function is to process...

of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer...

dendritic cells are tolerogenic. Conditions including the absence of an inflammatory environment result in the incomplete maturation of dendritic cells. Their...

their tolerogenic capabilities. Aside from dendritic cells, additional cell populations were identified that are able to induce antigen-specific T cell tolerance...

microenvironment determines if CD103+ dendritic cells act tolerogenic or immunogenic. The differentiation into regulatory T cells is dependent on TGFβ and retinoic...

2003). "High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells". Transplant Immunology. 11 (3–4): 245–258. doi:10.1016/S0966-3274(03)00058-3...

tolerance by allowing homing of tolerogenic dendritic cells to lymph nodes. CCR7 is expressed by various cancer cells, such as nonsmall lung cancer, gastric...

Isaacs JD, van Eden W, Hilkens CM (January 2018). "Targeting of tolerogenic dendritic cells towards heat-shock proteins: a novel therapeutic strategy for...

factors, research suggests that a lack of control by tolerogenic dendritic cells and T-regulatory cells (Treg) is possibly the primary risk factor for the...