In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial...
4 KB (447 words) - 16:04, 31 January 2021
The transactivation domain or trans-activating domain (TAD) is a transcription factor scaffold domain which contains binding sites for other proteins...
25 KB (2,773 words) - 08:32, 29 April 2024
Glucocorticoid (section Transactivation)
expression of anti-inflammatory proteins in the nucleus (a process known as transactivation) and represses the expression of pro-inflammatory proteins in the cytosol...
53 KB (5,544 words) - 20:09, 28 July 2024
Intrinsic activity (redirect from Relative transactivation capacity)
Intrinsic activity (IA) and efficacy refer to the relative ability of a drug-receptor complex to produce a maximum functional response. This must be distinguished...
10 KB (965 words) - 10:12, 12 January 2024
Transcription factor (redirect from Transactivation factor)
binding sites are frequently referred to as activation functions (AFs), Transactivation domain (TAD) or Trans-activating domain TAD, not to be confused with...
75 KB (8,057 words) - 04:44, 25 July 2024
Thiazolidinedione (section PPARĪ³ transactivation)
Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects....
20 KB (2,133 words) - 02:14, 29 July 2024
Glucocorticoid receptor (section Transactivation)
resulting activated form GR has two principal mechanisms of action, transactivation and transrepression, described below. A direct mechanism of action...
37 KB (4,035 words) - 09:01, 19 August 2024
mediators (transrepression) and inducing anti-inflammatory mediators (transactivation). Immunosuppressive effects are mediated by suppressing delayed hypersensitivity...
41 KB (4,147 words) - 01:54, 20 July 2024
promoter. Localised to the C-terminus, belongs to the nine amino acids transactivation domain family, 9aaTAD, together with Oaf1, Pip2, Pdr1, Pdr3, but also...
19 KB (2,205 words) - 12:40, 13 August 2023
modification through acetylation, which directly promotes AR-mediated transactivation, apoptosis and contact-independent growth of prostate cancer cells...
87 KB (9,376 words) - 13:18, 19 August 2024