Variant surface glycoprotein (VSG) is a ~60kDa protein which densely packs the cell surface of protozoan parasites belonging to the genus Trypanosoma...
31 KB (3,690 words) - 23:06, 13 August 2024
mammalian bloodstream forms are notable for their cell surface proteins, variant surface glycoproteins, which undergo remarkable antigenic variation, enabling...
107 KB (12,571 words) - 02:49, 29 July 2024
obstacles to development of such a vaccine. One obstacle is variant surface glycoprotein which makes it difficult for the immune system to recognize the...
4 KB (395 words) - 03:52, 29 November 2023
Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains. The carbohydrate is attached to...
28 KB (2,653 words) - 04:14, 23 July 2024
Rijsewijk FA, Borst P (June 1983). "The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements...
13 KB (1,517 words) - 23:39, 2 April 2024
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family...
35 KB (3,930 words) - 15:54, 5 August 2024
Antigenic variation (redirect from Variable surface antigen)
itself with a dense, homogeneous coat (~10^7 molecules) of the variant surface glycoprotein (VSG). In the early stages of invasion, the VSG coat is sufficient...
25 KB (3,270 words) - 05:30, 15 April 2024
Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are...
230 KB (21,225 words) - 03:06, 18 August 2024
antigenic variation. This is achieved through the switching of its variant surface glycoprotein or VSG, a substance that coats the entire antigen. When this...
14 KB (1,583 words) - 00:09, 12 August 2024
Coronavirus spike protein (section SARS-CoV-2 variants)
of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing...
76 KB (7,457 words) - 03:44, 17 June 2024