• Thumbnail for Variant surface glycoprotein
    Variant surface glycoprotein (VSG) is a ~60kDa protein which densely packs the cell surface of protozoan parasites belonging to the genus Trypanosoma...
    31 KB (3,690 words) - 23:06, 13 August 2024
  • Thumbnail for Trypanosoma brucei
    mammalian bloodstream forms are notable for their cell surface proteins, variant surface glycoproteins, which undergo remarkable antigenic variation, enabling...
    107 KB (12,571 words) - 02:49, 29 July 2024
  • obstacles to development of such a vaccine. One obstacle is variant surface glycoprotein which makes it difficult for the immune system to recognize the...
    4 KB (395 words) - 03:52, 29 November 2023
  • Thumbnail for Glycoprotein
    Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains. The carbohydrate is attached to...
    28 KB (2,653 words) - 04:14, 23 July 2024
  • Thumbnail for Exon
    Rijsewijk FA, Borst P (June 1983). "The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements...
    13 KB (1,517 words) - 23:39, 2 April 2024
  • Thumbnail for P-glycoprotein
    P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family...
    35 KB (3,930 words) - 15:54, 5 August 2024
  • itself with a dense, homogeneous coat (~10^7 molecules) of the variant surface glycoprotein (VSG). In the early stages of invasion, the VSG coat is sufficient...
    25 KB (3,270 words) - 05:30, 15 April 2024
  • Thumbnail for Variants of SARS-CoV-2
    Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are...
    230 KB (21,225 words) - 03:06, 18 August 2024
  • antigenic variation. This is achieved through the switching of its variant surface glycoprotein or VSG, a substance that coats the entire antigen. When this...
    14 KB (1,583 words) - 00:09, 12 August 2024
  • Thumbnail for Coronavirus spike protein
    of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing...
    76 KB (7,457 words) - 03:44, 17 June 2024