• 17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B) (EC 1.1.1.51), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which...
    31 KB (2,644 words) - 15:20, 12 May 2024
  • Thumbnail for 17β-Hydroxysteroid dehydrogenase III deficiency
    17β-Hydroxysteroid dehydrogenase III deficiency is a rare autosomal recessive disorder of sexual development condition that is a cause of 46,XY disorder...
    18 KB (1,408 words) - 14:04, 17 August 2024
  • Thumbnail for HSD17B2
    17β-Hydroxysteroid dehydrogenase 2 (17β-HSD2) is an enzyme of the 17β-hydroxysteroid dehydrogenase (17β-HSD) family that in humans is encoded by the HSD17B2...
    14 KB (1,715 words) - 15:06, 2 April 2024
  • 3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans...
    16 KB (1,731 words) - 18:00, 13 July 2024
  • Thumbnail for HSD17B1
    17β-Hydroxysteroid dehydrogenase 1 (17β-HSD1) is an enzyme that in humans is encoded by the HSD17B1 gene. This enzyme oxidizes or reduces the C17 hydroxy/keto...
    13 KB (1,581 words) - 03:14, 15 August 2024
  • Thumbnail for Spironolactone
    Spironolactone (category 17β-Hydroxysteroid dehydrogenase inhibitors)
    spironolactone has been found in vitro to act as a weak inhibitor of 17β-hydroxysteroid dehydrogenase 2, an enzyme that is involved in the conversion of estradiol...
    181 KB (17,316 words) - 05:17, 7 September 2024
  • Thumbnail for HSD17B3
    17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis....
    6 KB (747 words) - 15:07, 2 April 2024
  • Thumbnail for Androsterone
    it can be converted back into DHT via 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such...
    14 KB (1,235 words) - 15:21, 12 May 2024
  • Thumbnail for AKR1C3
    C3 (AKR1C3), also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5, HSD17B5) or 3α-hydroxysteroid dehydrogenase type 2 (3α-HSD2) is a steroidogenic...
    12 KB (1,528 words) - 15:02, 7 September 2024
  • Thumbnail for Testosterone
    3β-hydroxysteroid dehydrogenase to produce androstenedione. In the final and rate limiting step, the C17 keto group androstenedione is reduced by 17β-hydroxysteroid...
    149 KB (15,717 words) - 22:05, 8 September 2024