4-Hydroxycoumarins are a class of vitamin K antagonist (VKA) anticoagulant drug molecules. Chemically, they are derived from coumarin by adding a hydroxy...
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class of drugs. 4-Hydroxycoumarin forms the core of the chemical structure of anticoagulants known collectively as 4-hydroxycoumarins. They include, for...
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can cause birth defects (teratogens). Coumarins (more accurately 4-hydroxycoumarins) are the most commonly used VKAs. In medicine, the most commonly used...
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incorrectly referred to as "coumadins" rather than 4-hydroxycoumarins. Some of the 4-hydroxycoumarin anticoagulant class of chemicals are designed to have...
36 KB (2,940 words) - 20:34, 13 June 2024
Warfarin (category 4-Hydroxycoumarins)
Over the next few years, numerous similar chemicals (specifically 4-hydroxycoumarins with a large aromatic substituent at the 3 position) were found to...
94 KB (9,772 words) - 05:31, 19 April 2024
4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase. This enzyme...
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Hydroxycoumarin may refer to: 4-Hydroxycoumarin 7-Hydroxycoumarin (umbelliferone) This set index article lists chemical compounds articles associated...
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addition to this specific metabolic disruption, massive toxic doses of 4-hydroxycoumarin, 4-thiochromenone and 1,3-indandione anticoagulants cause damage to...
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Link, K. P. (1944). "Studies on 4-Hydroxycoumarins. V. The Condensation of α,β-Unsaturated Ketones with 4-Hydroxycoumarin". Journal of the American Chemical...
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deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin). Warfarin necrosis is a rare but severe complication...
11 KB (1,332 words) - 18:31, 11 March 2023