5-Hydroxymethylcytosine (5hmC) is a DNA pyrimidine nitrogen base derived from cytosine. It is potentially important in epigenetics, because the hydroxymethyl...
16 KB (1,744 words) - 17:52, 18 March 2024
Bisulfite sequencing (section 5-Hydroxymethylcytosine)
discovery of a new mammalian DNA modification 5-hydroxymethylcytosine. 5-Hydroxymethylcytosine converts to cytosine-5-methylsulfonate upon bisulfite treatment...
34 KB (4,084 words) - 21:59, 8 January 2024
methylated into 5-methylcytosine by an enzyme called DNA methyltransferase or be methylated and hydroxylated to make 5-hydroxymethylcytosine. The difference...
10 KB (906 words) - 09:52, 9 August 2024
for having invented TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method...
178 KB (18,218 words) - 21:17, 23 August 2024
demethylation, a series of oxidations converts it to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), and the latter two...
23 KB (2,630 words) - 19:42, 14 June 2024
standalone epigenetic marker. In mammals, 5fC is formed by oxidation of 5-Hydroxymethylcytosine (5hmC) a reaction mediated by TET enzymes. Its molecular formula...
9 KB (917 words) - 13:13, 24 May 2023
DNA 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and can further catalyse oxidation of 5hmC to 5-formylcytosine (5fC) and then to 5-carboxycytosine...
32 KB (3,984 words) - 05:42, 27 April 2024
Cell potency (redirect from PLETHORA 5)
in primordial germ cells via the initial conversion of 5mC to 5-hydroxymethylcytosine (5hmC), a reaction driven by high levels of the ten-eleven dioxygenase...
30 KB (3,291 words) - 18:55, 18 August 2024
to the invention of TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method...
12 KB (1,145 words) - 06:22, 16 February 2024
methylcytosine to 5-hydroxymethylcytosine. The first mechanistic reports showed tissue-specific accumulation of 5-hydroxymethylcytosine (5hmC) and the conversion...
25 KB (2,576 words) - 13:09, 21 January 2024