c-Met inhibitors are a class of small molecules that inhibit the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter...

of GRB2, phospholipase C γ (PLC-γ), p85, and SHP2. GAB1 is a key coordinator of the cellular responses to MET and binds the MET intracellular region with...

The Met Gala, formally called the Costume Institute Benefit, is the annual haute couture fundraising festival held for the benefit of the Metropolitan...

pregnancy. c-MET may interact with FoxM1, a molecule important in the cell cycle, as FOXM1 levels decrease when c-MET is not present. Additionally, c-MET may...

hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal...

muscular defects. Associated Genetic Factors: PAX3 and c-Met Mutations in PAX3 can cause a failure in c-Met expression. Such a mutation would result in a lack...

The New York Mets are an American professional baseball team based in the New York City borough of Queens. The Mets compete in Major League Baseball (MLB)...

The Meteorological Office, abbreviated as the Met Office, is the United Kingdom's national weather and climate service. It is an executive agency and...

Centre for Development of Advanced Computing (C-DAC) Centre for Materials for Electronics Technology (C-MET) National Institute of Electronics and Information...

treatment of non-small cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved...