tumor suppressor 2 (MTS-2) or p15INK4b is a protein that is encoded by the CDKN2B gene in humans. This gene lies adjacent to the tumor suppressor gene CDKN2A...
12 KB (1,386 words) - 16:05, 13 October 2024
CDKN2BAS (redirect from CDKN2B-AS1 (gene))
CDKN2B-AS, also known as ANRIL (antisense non-coding RNA in the INK4 locus) is a long non-coding RNA consisting of 19 exons, spanning 126.3kb in the genome...
13 KB (1,125 words) - 16:17, 13 October 2024
detected in 100%, 67%, 33% and 0% of cases, respectively. The CDKN2A (p16) and CDKN2B (p15) loci on chromosome 9p21 are frequently deleted in chordomas Another...
21 KB (2,201 words) - 19:15, 22 November 2024
interferon gene cluster and cyclin-dependent kinase inhibitors CDKN2A and CDKN2B in the genome. Although African green monkeys were previously classified...
7 KB (837 words) - 16:31, 14 April 2024
cancer genes including Kras, Nras, Trp53, Dcc, and Cacna1d. Cdkn2a and Cdkn2b are biallelically deleted from the genome. Five pathways (RTK/RAS, p53,...
11 KB (1,355 words) - 19:30, 6 April 2024
Another example is silencing of a tumor suppressor gene p15INK4b, also called CDKN2B, in acute lymphoblastic leukemia and acute myeloid leukemia. The asRNA that...
24 KB (2,997 words) - 00:53, 25 July 2024
T-cells), CDKN2A (encoding p16INK4a and p14arf tumor suppressor proteins) or CDKN2B (encoding cyclin dependent kinase inhibitor 2B multiple tumor suppressor...
68 KB (8,025 words) - 06:16, 29 December 2024
2690 CDKN2AIP HGNC:24325 Q9NXV6 2691 CDKN2AIPNL HGNC:30545 Q96HQ2 2692 CDKN2B HGNC:1788 P42772 2693 CDKN2C HGNC:1789 P42773 2694 CDKN2D HGNC:1790 P55273...
277 KB (17 words) - 18:34, 6 October 2024
Target p16 CDKN2A Cyclin-dependent kinase 4, Cyclin-dependent kinase 6 p15 CDKN2B Cyclin-dependent kinase 4 p18 CDKN2C Cyclin-dependent kinase 4, Cyclin-dependent...
10 KB (1,169 words) - 17:52, 15 August 2024
deletions in the NF1 gene occur ~10% of MFS cases while mutations in the CDKN2A/CDKN2B and amplifications in the CDK6, CCND1, and MDM2 genes occur in rare MFS...
20 KB (2,376 words) - 00:47, 11 January 2024