• Thumbnail for CDP-choline pathway
    The CDP-choline pathway, first identified by Eugene P. Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine...
    7 KB (932 words) - 16:46, 15 December 2022
  • Thumbnail for Citicoline
    diphosphate-choline (CDP-choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical...
    19 KB (1,857 words) - 18:39, 11 June 2024
  • Thumbnail for Phosphatidylethanolamine N-methyltransferase
    chromosome 17. While the CDP-choline pathway, in which choline obtained either by dietary consumption or by metabolism of choline-containing lipids is converted...
    31 KB (3,536 words) - 22:28, 27 March 2024
  • Thumbnail for Choline
    kidney. Choline-phosphate cytidylyltransferases (CPCT) transform PChol to CDP-choline (CDP-Chol) with cytidine triphosphate (CTP). CDP-choline and diglyceride...
    59 KB (6,147 words) - 07:19, 10 August 2024
  • Thumbnail for CHKA
    pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence...
    8 KB (977 words) - 08:04, 3 December 2023
  • Thumbnail for Phosphatidylcholine
    5'-diphosphocholine (CDP-choline or citicoline). The conversion is mediated by the enzyme diacylglycerol cholinephosphotransferase. Another pathway, mainly operative...
    11 KB (1,198 words) - 19:25, 7 February 2024
  • Thumbnail for Choline/ethanolamine kinase family
    phosphocholine by ethanolamine and choline kinases in the first step of the CDP-ethanolamine pathway. There are two putative choline/ethanolamine kinases (C/EKs)...
    3 KB (301 words) - 18:42, 22 December 2020
  • reaction CDP-diacylglycerol + choline ⇌ {\displaystyle \rightleftharpoons } CMP + phosphatidylcholine Thus, the two substrates of this enzyme are CDP-diacylglycerol...
    2 KB (168 words) - 15:22, 26 August 2023
  • Thumbnail for PCYT1B
    Choline-phosphate cytidylyltransferase B is an enzyme that in humans is encoded by the PCYT1B gene. GRCh38: Ensembl release 89: ENSG00000102230 – Ensembl...
    3 KB (410 words) - 23:46, 4 September 2022
  • Thumbnail for Diacylglycerol cholinephosphotransferase
    reaction CDP-choline + 1,2-diacylglycerol ⇌ {\displaystyle \rightleftharpoons } CMP + a phosphatidylcholine Thus, the two substrates of this enzyme are CDP-choline...
    4 KB (299 words) - 13:48, 26 August 2023