GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits. GABAA receptors including...
16 KB (1,639 words) - 05:16, 7 November 2023
Muscimol (category GABAA-rho receptor agonists)
selective GABAA agonist with exceptionally high affinity to GABAA-delta receptors, it is also a partial agonist at the GABAA-rho receptor, and so its...
37 KB (3,826 words) - 05:00, 11 August 2024
of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled...
35 KB (3,892 words) - 05:20, 16 May 2024
Allopregnanolone (category GABAA-rho receptor positive allosteric modulators)
is a neurosteroid and acts as a positive allosteric modulator of the GABAA receptor, the major biological target of the inhibitory neurotransmitter γ-aminobutyric...
50 KB (4,782 words) - 13:47, 19 July 2024
5α-Dihydroprogesterone (category GABAA-rho receptor negative allosteric modulators)
modulator of the GABAA-rho receptor. The steroid has been found to possess 82% of the affinity of progesterone for the progesterone receptor in rhesus monkey...
10 KB (909 words) - 23:12, 9 November 2023
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Its endogenous ligand is γ-aminobutyric acid (GABA), the major inhibitory...
54 KB (5,844 words) - 13:37, 26 July 2024
Gaboxadol (category GABAA-rho receptor antagonists)
α4β3δ GABAA receptors, low-potency agonist at α1β3γ2, and partial agonist at α4β3γ. Its affinity for this α4-containing subtype of the GABAA receptor is...
7 KB (550 words) - 21:38, 16 June 2024
Ibotenic acid (category GABAA-rho receptor agonists)
decarboxylation into muscimol, it acts indirectly as a potent GABAA and GABAA-ρ receptor agonist. Unlike muscimol—the principal psychoactive constituent...
16 KB (1,473 words) - 00:34, 20 July 2024
Bilobalide (category GABAA-rho receptor negative allosteric modulators)
been found to be a negative allosteric modulator at the GABAA and GABAA-rho receptors. Of GABAA, it may possibly be selective for the subunits predominantly...
7 KB (558 words) - 02:29, 26 June 2024
(+)-cis-2-Aminomethylcyclopropane carboxylic acid (category GABAA-rho receptor agonists)
(+)-cis-2-Aminomethylcyclopropane carboxylic acid ((+)-CAMP) is an agonist for the GABAA-rho receptor. "AC1LT400 - Compound Summary". PubChem Compound. USA: National Center...
3 KB (138 words) - 12:06, 18 September 2023