Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex...
7 KB (723 words) - 17:59, 15 May 2024
A mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid...
15 KB (1,466 words) - 09:36, 13 December 2023
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is...
14 KB (1,628 words) - 10:26, 5 January 2024
Aldosterone (category Mineralocorticoids)
Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. It is essential...
32 KB (3,377 words) - 13:20, 24 January 2024
in the treatment of hyperaldosteronism (high aldosterone levels or mineralocorticoid excess), for instance primary aldosteronism (Conn's syndrome)....
185 KB (18,143 words) - 07:11, 26 June 2024
disease associated with type 2 diabetes. Finerenone is a non-steroidal mineralocorticoid receptor antagonist (MRA). It is taken orally (swallowed by mouth)...
17 KB (1,448 words) - 10:26, 13 April 2024
Apparent mineralocorticoid excess is an autosomal recessive disorder causing hypertension (high blood pressure), hypernatremia (increased blood sodium...
12 KB (1,131 words) - 13:21, 9 March 2024
Congenital adrenal hyperplasia due to 17α-hydroxylase deficiency (section Mineralocorticoid effects)
synthesis of cortisol and sex hormones, with resulting increase in mineralocorticoid production. Thus, common symptoms include mild cortisol deficiency...
16 KB (1,830 words) - 22:53, 22 April 2024
Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency (section Mineralocorticoid effects)
the adrenal. 11β-OH CAH results in hypertension due to excessive mineralocorticoid effects. It also causes excessive androgen production both before...
10 KB (1,022 words) - 22:55, 5 January 2024
Eplerenone is an antimineralocorticoid, or an antagonist of the mineralocorticoid receptor (MR). Eplerenone is also known chemically as 9...
17 KB (1,476 words) - 06:07, 17 June 2024