phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic...
18 KB (1,886 words) - 04:23, 15 August 2024
It inhibits PDE4 to the greatest extent, but also shows significant inhibition of other PDE subtypes, and so acts as a selective PDE4 inhibitor or a...
22 KB (2,350 words) - 08:18, 3 June 2024
phenotypes can guide appropriate treatment approaches. For example, the PDE4 inhibitor roflumilast is targeted at the chronic-bronchitic phenotype. Two inflammatory...
159 KB (17,207 words) - 05:51, 15 August 2024
PDE4 inhibitor (found in Sceletium tortuosum (kanna)) Roxindole (EMD-49,980) (also a 5-HT1A and D2-like receptor agonist) Dopamine reuptake inhibitor...
11 KB (843 words) - 10:04, 13 March 2024
Phosphodiesterase 4 (redirect from PDE4)
phosphodiesterase 4 (PDE4) are known: PDE4A PDE4B PDE4C PDE4D 3',5'-cyclic-AMP phosphodiesterase Phosphodiesterase (PDE) PDE4 inhibitor This set index article...
290 bytes (59 words) - 11:15, 2 July 2022
Glaucine (category PDE4 inhibitors)
bronchodilator, neuroleptic and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive...
14 KB (1,401 words) - 03:49, 20 October 2023
phosphodiesterase 4 (PDE4) inhibitors like apremilast (a thalidomide derivative), roflumilast, and the less subtype-selective PDE4 inhibitor, pentoxifylline...
118 KB (12,901 words) - 19:42, 24 July 2024
Cereblon E3 ligase modulator (category PDE4 inhibitors)
hydroxyl and methoxy groups seem to make the analog a less potent PDE4 inhibitor. An increase in activity was observed with amino and dimethylamino to...
49 KB (5,487 words) - 11:41, 24 January 2024
Piclamilast (category PDE4 inhibitors)
Piclamilast (RP 73401), is a selective PDE4 inhibitor. It is comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated...
6 KB (542 words) - 23:19, 5 April 2023
Vardenafil Vardenafil dihydrochloride Vardenafil hydrochloride trihydrate Zaprinast Phosphodiesterase inhibitor This list was created from the NCI Thesaurus....
2 KB (137 words) - 00:17, 9 February 2024