Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer,...
61 KB (6,550 words) - 05:47, 5 August 2024
Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat...
9 KB (716 words) - 09:40, 4 August 2024
DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic acid (DHA), a fatty acid that...
5 KB (225 words) - 17:23, 30 April 2023
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an...
16 KB (1,961 words) - 04:43, 8 August 2024
of the drug with nab-paclitaxel on people with advanced TNBC concluded. Atezolizumab, in combination with bevacizumab, paclitaxel, and carboplatin, was...
43 KB (4,164 words) - 02:04, 16 July 2024
Paclitaxel trevatide (development codes NG1005 and GRN1005) is an experimental chemotherapy drug that is under development by Angiochem Inc, a Canadian...
15 KB (1,252 words) - 03:07, 17 November 2023
severe adverse effects. Docetaxel and paclitaxel have comparable efficacy metastatic breast cancer but paclitaxel has less severe side effects. Additionally...
44 KB (4,623 words) - 22:26, 10 May 2024
from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy agents...
7 KB (589 words) - 14:09, 24 April 2024
S. Food and Drug Administration approved protein-bound paclitaxel (also known as nab-paclitaxel, sold as Abraxane) used with gemcitabine. This regimen...
7 KB (711 words) - 16:46, 29 April 2024
source of paclitaxel. Other yew species contain similar compounds with similar biochemical activity. Docetaxel, an analogue of paclitaxel, is derived...
26 KB (2,514 words) - 01:40, 31 July 2024