• Thumbnail for RNF8
    E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. RNF8 has activity both in immune system functions and in DNA...
    18 KB (2,317 words) - 01:29, 3 December 2023
  • decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
    53 KB (5,924 words) - 18:51, 18 September 2024
  • Thumbnail for H2AFX
    but within 30 seconds of ionizing radiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
    22 KB (2,783 words) - 19:46, 2 October 2024
  • simultaneous accumulation of RNF8 protein and the DNA repair protein NBS1 which bind to MDC1 as MDC1 attaches to γH2AX. RNF8 mediates extensive chromatin...
    50 KB (5,523 words) - 09:43, 3 December 2023
  • Thumbnail for Homologous recombination
    decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
    106 KB (12,117 words) - 07:58, 5 October 2024
  • decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
    81 KB (10,099 words) - 11:45, 3 September 2024
  • Thumbnail for DNA repair
    decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
    129 KB (15,900 words) - 22:25, 12 October 2024
  • Thumbnail for BRCA1
    VCP is recruited to DNA lesions and cooperates with the ubiquitin ligase RNF8 to orchestrate assembly of signaling complexes for efficient DSB repair....
    121 KB (13,568 words) - 14:53, 22 October 2024
  • Thumbnail for Forkhead-associated domain
    domain solution structure of the fha domain of human ubiquitin ligase protein rnf8 Identifiers Symbol FHA Pfam PF00498 Pfam clan CL0357 InterPro IPR000253 PROSITE...
    3 KB (370 words) - 01:07, 18 June 2024
  • the binding of RNF8, a RING finger ubiquitin ligase to the E2 ubiquitin-conjugating enzyme UBC13. This association is required for RNF8 mediated Lys-63...
    27 KB (3,353 words) - 19:48, 8 October 2024