In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial...

The transactivation domain or trans-activating domain (TAD) is a transcription factor scaffold domain which contains binding sites for other proteins...

expression of anti-inflammatory proteins in the nucleus (a process known as transactivation) and represses the expression of pro-inflammatory proteins in the cytosol...

Intrinsic activity (IA) and efficacy refer to the relative ability of a drug-receptor complex to produce a maximum functional response. This must be distinguished...

binding sites are frequently referred to as activation functions (AFs), Transactivation domain (TAD) or Trans-activating domain TAD, not to be confused with...

Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects....

resulting activated form GR has two principal mechanisms of action, transactivation and transrepression, described below. A direct mechanism of action...

mediators (transrepression) and inducing anti-inflammatory mediators (transactivation). Immunosuppressive effects are mediated by suppressing delayed hypersensitivity...

modification through acetylation, which directly promotes AR-mediated transactivation, apoptosis and contact-independent growth of prostate cancer cells...

promoter. Localised to the C-terminus, belongs to the nine amino acids transactivation domain family, 9aaTAD, together with Oaf1, Pip2, Pdr1, Pdr3, but also...