Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
31 KB (3,370 words) - 18:46, 11 August 2024
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
44 KB (4,830 words) - 18:56, 11 August 2024
Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
60 KB (6,536 words) - 06:48, 29 August 2024
generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found...
50 KB (5,683 words) - 05:16, 29 June 2024
Biochemistry of Alzheimer's disease (redirect from Amyloid hypothesis)
and cingulate gyrus. Both amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in AD brains. Plaques are dense, mostly insoluble...
65 KB (7,761 words) - 09:06, 10 September 2024
Notably, amyloid plaques have been hypothesized to counteract this BBB leakage. However, upon the administration of antibodies, these plaques are targeted...
10 KB (780 words) - 07:19, 3 August 2024
of abnormally folded amyloid beta protein into amyloid plaques, and tau protein into neurofibrillary tangles in the brain. Plaques are made up of small...
183 KB (19,440 words) - 12:49, 30 September 2024
Atherosclerosis (redirect from Atherosclerotic plaques)
of atherosclerotic changes is similar to that in the development of amyloid plaques in the brain and that of age spots on the skin. Misrepair-accumulation...
100 KB (11,155 words) - 18:45, 24 August 2024
radiotracer developed for routine clinical application to visualize β-amyloid plaques in the brain. It is a fluorine-18 (18F)-labeled stilbene derivative...
17 KB (1,509 words) - 06:21, 1 July 2024
Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
18 KB (1,768 words) - 14:27, 21 August 2024