The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling...

different genes, signals, and a unique region of ectoderm called the apical ectodermal ridge (AER). Research by Saunders and Gasseling in 1948 identified the...

be a result of a wedge-shaped defect of the apical ectoderm of the limb bud (AER: apical ectodermal ridge). Polydactyly, syndactyly and cleft hand can...

between specialized ectodermal cells and the underlying mesoderm. Epithelial-mesenchymal interactions between the apical ectodermal ridge (AER) and the underlying...

anemia and TAR syndrome.Other possible causes are an injury to the apical ectodermal ridge during upper limb development, intrauterine compression, or maternal...

develop. Saunders researched the vertebrate limb and studied the apical ectodermal ridge (AER). This research was critical in recognizing growth factors...

and positive feedback retention of two signaling regions: the apical ectodermal ridge (AER) and the zone of polarizing activity (ZPA) with the mesenchymal...

lacrimal gland, tarsal glands, and the conjunctiva of the eye The apical ectodermal ridge, which induces the development of the limb buds of the embryo List...

Poland syndrome. Abnormality of an embryonic structure called the apical ectodermal ridge, which helps direct early limb development, may also be involved...

eventually becomes an apical ectodermal cap (AEC) that forms on the tip of the stump. This is similar to the embryonic apical ectodermal ridge, which forms during...