Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis)...
41 KB (4,564 words) - 10:38, 29 September 2024
The Bcl-2 family (TC# 1.A.21) consists of a number of evolutionarily-conserved proteins that share Bcl-2 homology (BH) domains. The Bcl-2 family is most...
16 KB (2,160 words) - 15:15, 1 October 2024
lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins...
7 KB (884 words) - 21:39, 24 July 2024
Inhibitor of apoptosis (section Bcl-2 family)
the mitochondria. The Bcl-2 family of proteins can either inhibit or promote apoptosis and members are characterized by the Bcl-2 homologous domains BH1...
13 KB (1,572 words) - 12:11, 13 September 2024
Apoptosis regulator BAX (redirect from Bcl-2–associated death protein)
regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family...
18 KB (2,092 words) - 06:47, 29 September 2024
gene bcl-2. Researchers had been hot in the track of oncogenes, and now more and more of the pieces were falling into place. However, although bcl-2 was...
12 KB (1,598 words) - 09:38, 22 June 2024
Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. The protein encoded by this gene is known to interact with cellular and...
10 KB (1,379 words) - 00:47, 2 December 2023
actress and singer Members of the Bcl-2 family, a group of related proteins involved in apoptosis, particularly bcl-2 Baltimore Catholic League Bangladesh...
2 KB (305 words) - 13:33, 20 September 2024
member of the Bcl-2 gene family which is involved in initiating apoptosis. BAD is a member of the BH3-only family, a subfamily of the Bcl-2 family. It does...
17 KB (1,980 words) - 03:17, 18 March 2024
Akt/PKB signaling pathway (redirect from PI/PI3K/AKT/BCL-2 pathway)
to the promoter of target genes, such as Bcl-2. Akt has also been shown to phosphorylate murine double minute 2 (Mdm2), a key regulator of DNA damage responses...
37 KB (4,145 words) - 21:50, 24 August 2024